Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Peptide
HGF
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938637
Quick Overview for Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Peptide (ABIN938637)
Target
HGF
(Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GESYRGLMDH TESGKICQRW DHQTPHRHKF LPERYPDKGF DDNYCRNPDG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of HGF antibody,
Alternative Names: HGF control peptide, HGF antibody Blocking Peptide, Anti-HGF Blocking Peptide, Hepatocyte Growth Factor Blocking Peptide, Hepapoietin A Scatter Factor Blocking Peptide, F-TCF Blocking Peptide, HGFB Blocking Peptide, HPTA Blocking Peptide, SF Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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Background
- Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69 kDa alpha-chain and 34 kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
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Molecular Weight
- 26 kDa
Target
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