Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) (Middle Region) Peptide
HGF
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all HGF products
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NENYCRNPDD DAHGPWCYTG NPLIPWDYCP ISRCEGDTTP TIVNLDHPVI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HGF Antibody(ARP44319_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
- Synonyms
- DFNB39 Peptide, F-TCF Peptide, HGFB Peptide, HPTA Peptide, SF Peptide, HGF Peptide, C230052L06Rik Peptide, HGF/SF Peptide, NK1 Peptide, NK2 Peptide, SF/HGF Peptide, hepatocyte growth factor Peptide, HGF Peptide, Hgf Peptide
- Background
-
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69- kDa alpha-chain and 34- kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
Alias Symbols: F-TCF, HGFB, HPTA, SF, DFNB39
Protein Interaction Partner: MET,CLEC3B,F11,FN1,HGF,HGFAC,HPN,KLKB1,LCN2,MET,PLAU,SDC1,SDC2,ST14,VTN,CLEC3B,HGF,MET,NRP1,SDC1,SDC2
Protein Size: 723 - Molecular Weight
- 79 kDa
- Gene ID
- 3082
- NCBI Accession
- NM_001010932, NP_001010932
- UniProt
- P14210
-
You are here:
