Centromere Protein B (CENPB) Peptide
CENPB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all CENPB products
- CENPB (Centromere Protein B (CENPB))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CENPB antibody,
Alternative Names: CENPB control peptide, CENPB antibody Blocking Peptide, Anti-CENPB Blocking Peptide, Centromere Protein B 80Kda Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- CENPB (Centromere Protein B (CENPB))
- Synonyms
- CENPB Peptide, CENP-B Peptide, centromere protein B Peptide, centromere protein B, 80kDa Peptide, CENPB Peptide, Cenpb Peptide
- Background
- CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognised by sera from patients with anti-centromere antibodies.
- Molecular Weight
- 65 kDa
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