RNA Binding Motif Protein 5 (RBM5) Peptide
RBM5
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938939
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for RNA Binding Motif Protein 5 (RBM5) Peptide (ABIN938939)
Target
RBM5
(RNA Binding Motif Protein 5 (RBM5))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- GSDKRVSRTE RSGRYGSIID RDDRDERESR SRRRDSDYKR SSDDRRGDRY
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of RBM5 antibody,
Alternative Names: RBM5 control peptide, RBM5 antibody Blocking Peptide, Anti-RBM5 Blocking Peptide, RNA binding motif protein 5 Blocking Peptide, FLJ39876 Blocking Peptide, G15 Blocking Peptide, H37 Blocking Peptide, LUCA15 Blocking Peptide, RMB5 Blocking Peptide, RBM5, RBM-5, RBM 5, RBM-5 Blocking Peptide, RBM 5 Blocking Peptide
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- RBM5 (RNA Binding Motif Protein 5 (RBM5))
-
Background
- RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
-
Molecular Weight
- 92 kDa
Target
-
You are here:
