RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptide
RBM5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982753
$160.46
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100 μg
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United States
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Quick Overview for RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptide (ABIN982753)
Target
RBM5
(RNA Binding Motif Protein 5 (RBM5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RBM5 antibody (Catalog #: ARP38684_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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Background
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RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5
Protein Interaction Partner: C1orf103,C1orf103
Protein Size: 815 -
Molecular Weight
- 92 kDa
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Gene ID
- 10181
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NCBI Accession
- NM_005778, NP_005769
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UniProt
- P52756
Target
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