N-Acylaminoacyl-Peptide Hydrolase (APEH) Peptide
APEH
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938976
Quick Overview for N-Acylaminoacyl-Peptide Hydrolase (APEH) Peptide (ABIN938976)
Target
APEH
(N-Acylaminoacyl-Peptide Hydrolase (APEH))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GSTGFGQDSI LSLPGNVGHQ DVKDVQFAVE QVLQEEHFDA SHVALMGGSH
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of APEH antibody,
Alternative Names: APEH control peptide, APEH antibody Blocking Peptide, Anti-APEH Blocking Peptide, N-Acylaminoacyl-Peptide Hydrolase Blocking Peptide, ACPH Blocking Peptide, APH Blocking Peptide, D3F15S2 Blocking Peptide, D3S48E Blocking Peptide, DNF15S2 Blocking Peptide, MGC2178 Blocking Peptide, OPH Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))
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Background
- APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
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Molecular Weight
- 81 kDa
Target
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