Premelanosome Protein (PMEL) Peptide
PMEL
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN939113
Quick Overview for Premelanosome Protein (PMEL) Peptide (ABIN939113)
Target
Melanoma gp100 (PMEL)
(Premelanosome Protein (PMEL))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SILV antibody,
Alternative Names: SILV control peptide, SILV antibody Blocking Peptide, Anti-SILV Blocking Peptide, Silver Homolog Blocking Peptide, D12S53E Blocking Peptide, ME20 Blocking Peptide, PMEL17 Blocking Peptide, SI Blocking Peptide, SIL Blocking Peptide, gp100 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Background
- SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
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Molecular Weight
- 70 kDa
Target
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