Premelanosome Protein (PMEL) Peptide
PMEL
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
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- Target See all Melanoma gp100 (PMEL) products
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- HFLRNQPLTF ALQLHDPSGY LAEADLSYTW DFGDSSGTLI SRALVVTHTY
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SILV antibody,
Alternative Names: SILV control peptide, SILV antibody Blocking Peptide, Anti-SILV Blocking Peptide, Silver Homolog Blocking Peptide, D12S53E Blocking Peptide, ME20 Blocking Peptide, PMEL17 Blocking Peptide, SI Blocking Peptide, SIL Blocking Peptide, gp100 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Background
- SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
- Molecular Weight
- 70 kDa
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