FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide
FGD1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all FGD1 products
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of FGD1 antibody,
Alternative Names: FGD1 control peptide, FGD1 antibody Blocking Peptide, Anti-FGD1 Blocking Peptide, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia Blocking Peptide, AAS Blocking Peptide, FGDY Blocking Peptide, ZFYVE3 Blocking Peptide, FGD1, FGD-1, FGD 1, FGD-1 Blocking Peptide, FGD 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Synonyms
- AAS Peptide, FGDY Peptide, MRXS16 Peptide, ZFYVE3 Peptide, FYVE, RhoGEF and PH domain containing 1 Peptide, FGD1 Peptide, Fgd1 Peptide, fgd1 Peptide
- Background
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs.
- Molecular Weight
- 106 kDa
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