Glutamate Receptor, Metabotropic 7 (GRM7) Peptide
GRM7
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939194
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Glutamate Receptor, Metabotropic 7 (GRM7) Peptide (ABIN939194)
Target
GRM7
(Glutamate Receptor, Metabotropic 7 (GRM7))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GRM7 antibody,
Alternative Names: GRM7 control peptide, GRM7 antibody Blocking Peptide, Anti-GRM7 Blocking Peptide, glutamate receptor, metabotropic 7 Blocking Peptide, FLJ40498 Blocking Peptide, GLUR7 Blocking Peptide, GPRC1G Blocking Peptide, MGLU7 Blocking Peptide, MGLUR7 Blocking Peptide, GRM7, GRM-7, GRM 7, GRM-7 Blocking Peptide, GRM 7 Blocking Peptide
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Glutamate Receptor, Metabotropic 7 (GRM7) peptide
GRM7 Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
Glutamate Receptor, Metabotropic 7 (GRM7) peptideGRM7 Host: Synthetic BP, WB, IHC
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Background
- L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 99 kDa
Target
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