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Protocadherin-15 (PCDH15) Peptide

PCDH15 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939239

Quick Overview for Protocadherin-15 (PCDH15) Peptide (ABIN939239)

Target

PCDH15 (Protocadherin-15 (PCDH15))

Origin

Mammalian

Source

  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    HSIVVQVQCI NKKVGTIIYH EVRIVVRDRN DNSPTFKHES YYATVNELTP

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of PCDH15 antibody,
    Alternative Names: PCDH15 control peptide, PCDH15 antibody Blocking Peptide, Anti-PCDH15 Blocking Peptide, Protocadherin 15 Blocking Peptide, RP.2 Blocking Peptide, DFNB23 Blocking Peptide, DKFZp667A1711 Blocking Peptide, USH1F Blocking Peptide, PCDH15, PCDH-15, PCDH 15, PCDH-15 Blocking Peptide, PCDH 15 Blocking Peptide

    Purification

    Serum
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    PCDH15 (Protocadherin-15 (PCDH15))

    Background

    PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

    Molecular Weight

    80 kDa
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