Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) Peptide
MAP2K2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all MEK2 (MAP2K2) products
- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- IKNPAERADL KMLTNHTFIK RSEVEEVDFA GWLCKTLRLN QPGTPTRTAV
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAP2 K2 antibody,
Alternative Names: MAP2K2 control peptide, MAP2K2 antibody Blocking Peptide, Anti-MAP2K2 Blocking Peptide, Mitogen-Activated Protein Kinase 2 Blocking Peptide, MAPKK2 Blocking Peptide, MEK2 Blocking Peptide, MKK2 Blocking Peptide, PRKMK2 Blocking Peptide, MAP2, MAP-2, MAP 2, MAP-2 Blocking Peptide, MAP 2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
- Synonyms
- CFC4 Peptide, MAPKK2 Peptide, MEK2 Peptide, MKK2 Peptide, PRKMK2 Peptide, AA589381 Peptide, MK2 Peptide, Prkmk2 Peptide, ATMKK2 Peptide, F27B13.50 Peptide, F27B13_50 Peptide, MAP KINASE KINASE 1 Peptide, MAP kinase kinase 2 Peptide, MK1 Peptide, map2k2 Peptide, wu:fa56c06 Peptide, zgc:123171 Peptide, zgc:172250 Peptide, mitogen-activated protein kinase kinase 2 Peptide, mitogen activated protein kinase kinase 2 Peptide, MAP kinase kinase 2 Peptide, mitogen-activated protein kinase kinase 2a Peptide, mitogen-activated protein kinase kinase 2b Peptide, MAP2K2 Peptide, Map2k2 Peptide, MKK2 Peptide, map2k2a Peptide, map2k2b Peptide
- Background
- MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
- Molecular Weight
- 44 kDa
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