Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Peptide
Quick Overview for Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Peptide (ABIN939511)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- IQSMNYGTIK WFFHVIIFSY VCFALVSDKL YQRKEPVISS VHTKVKGIAE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of P2 RX7 antibody,
Alternative Names: P2RX7 control peptide, P2RX7 antibody Blocking Peptide, Anti-P2RX7 Blocking Peptide, Purinergic Receptor P2X Ligand-Gated Ion Channel 7 Blocking Peptide, P2RX7, PRX7-2, PRX7 2, PRX7-2 Blocking Peptide, PRX7 2 Blocking Peptide -
Purification
- Purified mouse LN B cells (C3H anti-C57Bl6)
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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Background
- The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
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Molecular Weight
- 31 kDa
Target
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