O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptide
MGMT
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all MGMT products
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MGMT antibody,
Alternative Names: MGMT control peptide, MGMT antibody Blocking Peptide, Anti-MGMT Blocking Peptide, O-6-MethylRNA guanine-Dna Methyltransferase Blocking Peptide - Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Synonyms
- AGT Peptide, AI267024 Peptide, Agat Peptide, O-6-methylguanine-DNA methyltransferase Peptide, MGMT Peptide, Mgmt Peptide
- Background
- MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- Molecular Weight
- 22 kDa
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