Cyclin D1 (CCND1) Peptide
CCND1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Cyclin D1 (CCND1) products
- Cyclin D1 (CCND1)
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KCEEEVFPLA MNYLDRFLSL EPVKKSRLQL LGATCMFVAS KMKETIPLTA
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CCND1 antibody,
Alternative Names: CCND1 control peptide, CCND1 antibody Blocking Peptide, Anti-CCND1 Blocking Peptide, cyclin D1 Blocking Peptide, BCL1 Blocking Peptide, D11S287E Blocking Peptide, PRAD1 Blocking Peptide, U21B31 Blocking Peptide, CCND1, CCND-1, CCND 1, CCND-1 Blocking Peptide, CCND 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Cyclin D1 (CCND1)
- Synonyms
- BCL1 Peptide, D11S287E Peptide, PRAD1 Peptide, U21B31 Peptide, AI327039 Peptide, CycD1 Peptide, Cyl-1 Peptide, bcl-1 Peptide, cD1 Peptide, cb161 Peptide, cycd1 Peptide, etID37810.7 Peptide, fb52e01 Peptide, fc45c08 Peptide, fc83a12 Peptide, id:ibd1198 Peptide, wu:fb52e01 Peptide, wu:fc45c08 Peptide, wu:fc83a12 Peptide, ccnd1b Peptide, prad1 Peptide, ccnd1 Peptide, ccnd1a Peptide, bcl1 Peptide, d11s287e Peptide, u21b31 Peptide, CCND1 Peptide, cyclin D1 Peptide, cyclin D1 S homeolog Peptide, cyclin D1 L homeolog Peptide, CCND1 Peptide, Ccnd1 Peptide, ccnd1 Peptide, ccnd1.S Peptide, ccnd1.L Peptide
- Background
- CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
- Molecular Weight
- 34 kDa
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