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Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) Peptide

MAPKAPK3 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939713
  • Target See all MAPKAP Kinase 3 (MAPKAPK3) products
    MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KEEMTSALAT MRVDYDQVKI KDLKTSNNRL LNKRRKKQAG SSSASQGCNN
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of MAPKAPK3 antibody,
    Alternative Names: MAPKAPK3 control peptide, MAPKAPK3 antibody Blocking Peptide, Anti-MAPKAPK3 Blocking Peptide, mitogen-activated protein kinase-activated protein kinase 3 Blocking Peptide, 3PK Blocking Peptide, MAPKAP3 Blocking Peptide, MAPKAPK3, MAPKAPK-3, MAPKAPK 3, MAPKAPK-3 Blocking Peptide, MAPKAPK 3 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
    Synonyms
    3PK Peptide, MAPKAP-K3 Peptide, MAPKAP3 Peptide, MAPKAPK-3 Peptide, MK-3 Peptide, AI874665 Peptide, MK3 Peptide, MapkKapk3 Peptide, MAPKAPK3 Peptide, mapkapk3 Peptide, MGC154360 Peptide, 3pk Peptide, mapkap3 Peptide, zgc:158342 Peptide, mitogen-activated protein kinase-activated protein kinase 3 Peptide, mitogen-activated protein kinase-activated protein kinase 3 S homeolog Peptide, MAPKAPK3 Peptide, Mapkapk3 Peptide, mapkapk3.S Peptide, mapkapk3 Peptide
    Background
    MAPKAPK3 is a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
    Molecular Weight
    43 kDa
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