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RAN Binding Protein 1 (RANBP1) Peptide

RANBP1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939753
  • Target See all RANBP1 products
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of RANBP1 antibody,
    Alternative Names: RanBP1 control peptide, RanBP1 antibody Blocking Peptide, Anti-RanBP1 Blocking Peptide, Ran Binding Protein 1 Blocking Peptide, MGC88701 Blocking Peptide, RanBP1, RanBP-1, RanBP 1, RanBP-1 Blocking Peptide, RanBP 1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Synonyms
    MGC64314 Peptide, zeh1094 Peptide, zgc:85649 Peptide, hm:zeh1094 Peptide, wu:fa96a09 Peptide, wu:fj39g07 Peptide, HTF9A Peptide, Htf9a Peptide, RAN binding protein 1 S homeolog Peptide, RAN binding protein 1 L homeolog Peptide, ran binding protein 1 Peptide, RAN binding protein 1 Peptide, ran-specific GTPase-activating protein pseudogene Peptide, ranbp1.S Peptide, ranbp1.L Peptide, PVX_090070 Peptide, GL50803_16969 Peptide, LOC100343953 Peptide, ranbp1 Peptide, RANBP1 Peptide, Ranbp1 Peptide
    Background
    Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
    Molecular Weight
    23 kDa
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