Peptidase Inhibitor 3, Skin-Derived (PI3) Peptide
PI3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all PI3 products
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PI3 antibody,
Alternative Names: PI3 control peptide, PI3 antibody Blocking Peptide, Anti-PI3 Blocking Peptide, Peptidase Inhibitor 3 Skin-Derived Blocking Peptide, Skalp Blocking Peptide, ESI Blocking Peptide, MGC13613 Blocking Peptide, SKALP Blocking Peptide, WAP3 Blocking Peptide, WFDC14 Blocking Peptide, PI3, PI-3, PI 3, PI-3 Blocking Peptide, PI 3 Blocking Peptide - Purification
- Supernatant
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
- Synonyms
- ESI Peptide, SKALP Peptide, WAP3 Peptide, WFDC14 Peptide, cementoin Peptide, trappin-2 Peptide, TRAPPIN-2 Peptide, elafin Peptide, peptidase inhibitor 3 Peptide, peptidase inhibitor 3, skin-derived (SKALP) Peptide, PI3 Peptide
- Background
- PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
- Molecular Weight
- 6 kDa
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