Actin-Like 7b (Actl7b) Peptide
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- Target See all Actl7b products
- Actl7b (Actin-Like 7b (Actl7b))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KLITIGQERF RCSEMLFQPS LAGSTQPGLP ELTAACLGRC QDTGFKEEMA
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTL7 B antibody,
Alternative Names: ACTL7B control peptide, ACTL7B antibody Blocking Peptide, Anti-ACTL7B Blocking Peptide, Actin-Like 7B Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Actl7b (Actin-Like 7b (Actl7b))
- Synonyms
- ACTL7B Peptide, Tact1 Peptide, actin-like 7b Peptide, actin like 7B Peptide, Actl7b Peptide, ACTL7B Peptide
- Background
- ACTL7B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
- Molecular Weight
- 46 kDa
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