Prohibitin 2 (PHB2) Peptide
PHB2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939919
Quick Overview for Prohibitin 2 (PHB2) Peptide (ABIN939919)
Target
Prohibitin 2 (PHB2)
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KLRKIRAAQN ISKTIATSQN RIYLTADNLV LNLQDESFTR GSDSLIKGKK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PHB2 antibody,
Alternative Names: Prohibitin 2 control peptide, Prohibitin 2 antibody Blocking Peptide, Anti-Prohibitin 2 Blocking Peptide, BAP Blocking Peptide, BCAP37 Blocking Peptide, Bap37 Blocking Peptide, MGC117268 Blocking Peptide, PNAS-141 Blocking Peptide, REA Blocking Peptide, p22 Blocking Peptide, PHB2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Prohibitin 2 (PHB2)
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Background
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
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Molecular Weight
- 33 kDa
Target
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