Prohibitin 2 (PHB2) Peptide
PHB2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Prohibitin 2 (PHB2) products
- Prohibitin 2 (PHB2)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHB2 antibody (Catalog #: ARP48316_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Prohibitin 2 (PHB2)
- Synonyms
- bcap37 Peptide, zgc:73150 Peptide, wu:fc28c08 Peptide, PHB2 Peptide, phb2 Peptide, ATPHB2 Peptide, F21M11.21 Peptide, F21M11_21 Peptide, prohibitin 2 Peptide, DKFZp469N1310 Peptide, BAP Peptide, BCAP37 Peptide, Bap37 Peptide, PNAS-141 Peptide, REA Peptide, p22 Peptide, bap37 Peptide, prohibitin2 Peptide, xphb2 Peptide, AU044498 Peptide, Bcap37 Peptide, Bap Peptide, Bap-37 Peptide, Bcap27 Peptide, prohibitin 2a Peptide, prohibitin 2 Peptide, prohibitin 2 S homeolog Peptide, phb2a Peptide, PHB2 Peptide, phb2 Peptide, phb2.S Peptide, Phb2 Peptide
- Background
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PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.
Alias Symbols: BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Protein Interaction Partner: ESR1,PTMA,AKT1,ESR1,HDAC1,HDAC2,HDAC3,HDAC5,MEF2A,MYOD1,PTMA,UPF2,CDC25B,COPG,CTNNB1,DDX20,EPPK1,ESR1,JUP,LGALS3BP,MMS19,NUP205,NUP93,PDXDC1,PTMA,RIPK2,RUNX3,SERINC3,SIRT2,TFE3,TH1L,TIMM50,USP15
Protein Size: 299 - Molecular Weight
- 33 kDa
- Gene ID
- 11331
- NCBI Accession
- NM_007273, NP_009204
- UniProt
- Q99623
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