Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) Peptide
GCLM
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN939978
Quick Overview for Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) Peptide (ABIN939978)
Target
GCLM
(Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- KPNSNQVNLA SCCVMPPDLT AFAKQFDIQL LTHNDPKELL SEASFQEALQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GCLM antibody,
Alternative Names: GCLM control peptide, GCLM antibody Blocking Peptide, Anti-GCLM Blocking Peptide, Glutamate-Cysteine Ligase Modifier Subunit Blocking Peptide, GLCLR Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
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Background
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis.
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Molecular Weight
- 31 kDa
Target
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