Glutamate-Cysteine Ligase, Modifier Subunit (GCLM) Peptide
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- Target See all GCLM products
- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GCLM antibody (Catalog #: ARP54624_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
- Synonyms
- Glclr Peptide, GLCLR Peptide, id:ibd3182 Peptide, wu:fi24c07 Peptide, zgc:55903 Peptide, AI649393 Peptide, Gcmc Peptide, glutamate-cysteine ligase regulatory subunit Peptide, glutamate cysteine ligase, modifier subunit Peptide, glutamate-cysteine ligase modifier subunit Peptide, glutamate-cysteine ligase, modifier subunit Peptide, glutamate-cysteine ligase, modifier subunit L homeolog Peptide, PTRG_09814 Peptide, Gclm Peptide, GCLM Peptide, gclm Peptide, gclm.L Peptide
- Background
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Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GLCLR
Protein Size: 274 - Molecular Weight
- 31 kDa
- Gene ID
- 2730
- NCBI Accession
- NM_002061, NP_002052
- UniProt
- P48507
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