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GRB2-Related Adaptor Protein (GRAP) Peptide

GRAP Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940020
  • Target See all GRAP products
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of GRAP antibody,
    Alternative Names: GRAP control peptide, GRAP antibody Blocking Peptide, Anti-GRAP Blocking Peptide, Grb2-Related Adaptor Protein Blocking Peptide, MGC64880 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Synonyms
    8430435N19Rik Peptide, BB233594 Peptide, GRAP Peptide, grap Peptide, zgc:110202 Peptide, MGC109892 Peptide, si:dkeyp-9d4.1 Peptide, Grap Peptide, GRB2-related adaptor protein Peptide, GRB2-related adapter protein Peptide, GRB2-related adaptor protein a Peptide, GRB2-related adaptor protein b Peptide, GRAP Peptide, Grap Peptide, LOC489534 Peptide, grapa Peptide, grapb Peptide, LOC100727005 Peptide
    Background
    This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
    Molecular Weight
    25 kDa
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