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Apolipoprotein E (APOE) Peptide

APOE Reactivity: Mammalian Host: Synthetic BP, IHC, WB
Catalog No. ABIN940102

Quick Overview for Apolipoprotein E (APOE) Peptide (ABIN940102)

Target

APOE (Apolipoprotein E (APOE))

Origin

Mammalian

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Peptide Type

    Synthetic

    Sequence

    KVLWAALLVT FLAGCQAKVE QAVETEPEPE LRQQTEWQSG QRWELALGRF

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of APOE antibody,
    Alternative Names: ApoE control peptide, ApoE antibody Blocking Peptide, Anti-ApoE Blocking Peptide, Apolipoprotein E Blocking Peptide, AD2 Blocking Peptide, MGC1571 Blocking Peptide, apoprotein Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    APOE (Apolipoprotein E (APOE))

    Background

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    Molecular Weight

    34 kDa
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