Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) Peptide
PSMD12
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940128
Quick Overview for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12) Peptide (ABIN940128)
Target
PSMD12
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KYKDLLKLFT TMELMRWSTL VEDYGMELRK GSLESPATDV FGSTEEGEKR
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PSMD12 antibody,
Alternative Names: PSMD12 control peptide, PSMD12 antibody Blocking Peptide, Anti-PSMD12 Blocking Peptide, Proteasome macropain 26S subunit non-ATPase 12 Blocking Peptide, Prosome Macropain 26S Subunit Non-Atpase 12 Blocking Peptide, MGC75406 Blocking Peptide, p55 Blocking Peptide, PSMD12, PSMD-12, PSMD 12, PSMD-12 Blocking Peptide, PSMD 12 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.
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Molecular Weight
- 53 kDa
Target
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