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Crystallin, alpha B (CRYAB) Peptide

CRYAB Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940136
  • Target See all CRYAB products
    CRYAB (Crystallin, alpha B (CRYAB))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of CRYAB antibody,
    Alternative Names: Crystallin Alpha B control peptide, Crystallin Alpha B antibody Blocking Peptide, Anti-Crystallin Alpha B Blocking Peptide, CRYAB Blocking Peptide, CRYA2 Blocking Peptide, CTPP2 Blocking Peptide, HSPB5 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    CRYAB (Crystallin, alpha B (CRYAB))
    Synonyms
    CMD1II Peptide, CRYA2 Peptide, CTPP2 Peptide, CTRCT16 Peptide, HSPB5 Peptide, MFM2 Peptide, Crya-2 Peptide, Crya2 Peptide, HspB5 Peptide, AACRYA Peptide, CRYAB Peptide, cryab Peptide, cryab2 Peptide, wu:fe37f08 Peptide, zgc:91937 Peptide, crystallin alpha B Peptide, crystallin, alpha B Peptide, hypothetical protein Peptide, crystallin, alpha B, a Peptide, crystallin, alpha B, b Peptide, CRYAB Peptide, Cryab Peptide, ZK1128.7 Peptide, cryaba Peptide, cryabb Peptide
    Background
    Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
    Molecular Weight
    12 kDa
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