Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Peptide
SUV39H2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all SUV39H2 products
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LDTRLPRIAL FSTRTINAGE ELTFDYQMKG SGDISSDSID HSPAKKRVRT
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SUV39 H2 antibody,
Alternative Names: SUV39H2 control peptide, SUV39H2 antibody Blocking Peptide, Anti-SUV39H2 Blocking Peptide, Suppressor Of Variegation 3-9 Homolog 2 Blocking Peptide, FLJ23414 Blocking Peptide, KMT1B Blocking Peptide, SUV39H2, SUVH2-39, SUVH2 39, SUVH2-39 Blocking Peptide, SUVH2 39 Blocking Peptide
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Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) peptide
SUV39H2 Reactivity: Human, Pig, Cow, Dog, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
- Synonyms
- KMT1B Peptide, 4930507K23Rik Peptide, AA536750 Peptide, D030054H19Rik Peptide, D2Ertd544e Peptide, SUV39H2 Peptide, kmt1b Peptide, suppressor of variegation 3-9 homolog 2 Peptide, suppressor of variegation 3-9 homolog 2 (Drosophila) Peptide, suppressor of variegation 3-9 homolog 2 L homeolog Peptide, SUV39H2 Peptide, Suv39h2 Peptide, suv39h2 Peptide, suv39h2.L Peptide
- Background
- SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.
- Molecular Weight
- 40 kDa
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