Leptin (LEP) Peptide
LEP
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
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- Target See all Leptin (LEP) products
- Leptin (LEP)
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- LHVLAFSKSC HLPWASGLET LDSLGGVLEA SGYSTEVVAL SRLQGSLQDM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of LEP antibody,
Alternative Names: Leptin control peptide, Leptin antibody Blocking Peptide, Anti-Leptin Blocking Peptide, OB Blocking Peptide, OBS Blocking Peptide, LEP Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Leptin (LEP)
- Synonyms
- ob Peptide, obese Peptide, LEPD Peptide, OB Peptide, OBS Peptide, leptin Peptide, Lep Peptide, LEP Peptide, lep Peptide
- Background
- LEP is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
- Molecular Weight
- 16 kDa
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