Actinin, alpha 4 (ACTN4) Peptide
ACTN4
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all alpha Actinin 4 (ACTN4) products
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM LDAEDIVNTA
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN4 antibody,
Alternative Names: alpha Actinin 4 control peptide, alpha Actinin 4 antibody Blocking Peptide, Anti-alpha Actinin 4 Blocking Peptide, ACTN4 Blocking Peptide, DKFZp686K23158 Blocking Peptide, FSGS Blocking Peptide, FSGS1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Synonyms
- fsgs Peptide, fsgs1 Peptide, C77391 Peptide, ACTININ-4 Peptide, FSGS Peptide, FSGS1 Peptide, wu:fb53f05 Peptide, zgc:63508 Peptide, actinin alpha 4 Peptide, actinin, alpha 4 Peptide, actinin alpha 4 S homeolog Peptide, actn4 Peptide, ACTN4 Peptide, Actn4 Peptide, actn4.S Peptide
- Background
- Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
- Molecular Weight
- 100 kDa
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