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ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B) Peptide

ACTR1B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972874
  • Target See all ACTR1B products
    ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ACTR1B antibody (Catalog #: ARP52099_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin beta (ACTR1B))
    Synonyms
    ARP1B Peptide, CTRN2 Peptide, PC3 Peptide, 2310066K23Rik Peptide, AA960180 Peptide, AI851923 Peptide, Arp1b Peptide, ACTR1B Peptide, ARP1 actin related protein 1 homolog B Peptide, ARP1 actin-related protein 1B, centractin beta Peptide, ARP1 actin-related protein 1 homolog B Peptide, ARP1 actin-related protein 1 homolog B, centractin beta (yeast) Peptide, beta-centractin Peptide, ACTR1B Peptide, Actr1b Peptide, LOC100594459 Peptide
    Background
    ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90 % amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90 % amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.

    Alias Symbols: ARP1B, CTRN2, PC3

    Protein Interaction Partner: ACTA1,CHD3,DCTN1

    Protein Size: 376
    Molecular Weight
    42 kDa
    Gene ID
    10120
    NCBI Accession
    NM_005735, NP_005726
    UniProt
    P42025
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