Acylglycerol Kinase (AGK) (N-Term) Peptide
AGK
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972993
Quick Overview for Acylglycerol Kinase (AGK) (N-Term) Peptide (ABIN972993)
Target
Acylglycerol Kinase (AGK)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- DNLLRRAACQ EAQVFGNQLI PPNAQVKKAT VFLNPAACKG KARTLFEKNA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AGK Antibody(ARP57169_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Acylglycerol Kinase (AGK) peptide
AGK Reactivity: Human, Mouse Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Acylglycerol Kinase (AGK)
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Background
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AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: HCK,PDLIM1,SNX4
Protein Size: 422 -
Molecular Weight
- 47 kDa
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Gene ID
- 55750
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NCBI Accession
- NM_018238, NP_060708
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UniProt
- Q53H12
Target
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