Acylglycerol Kinase (AGK) (N-Term) Peptide
AGK
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Acylglycerol Kinase (AGK) products
- Acylglycerol Kinase (AGK)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AGK Antibody(ARP57170_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Acylglycerol Kinase (AGK) peptide
AGK Reactivity: Human, Mouse Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Acylglycerol Kinase (AGK)
- Synonyms
- mulk Peptide, CATC5 Peptide, CTRCT38 Peptide, MTDPS10 Peptide, MULK Peptide, 2610037M15Rik Peptide, 6720408I04Rik Peptide, AI465370 Peptide, Mulk Peptide, RGD1562046 Peptide, fi38e09 Peptide, wu:fi38e09 Peptide, zgc:55462 Peptide, acylglycerol kinase Peptide, acylglycerol kinase S homeolog Peptide, AGK Peptide, agk Peptide, LOC100165096 Peptide, Agk Peptide, agk.S Peptide
- Background
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AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: HCK,PDLIM1,SNX4
Protein Size: 422 - Molecular Weight
- 47 kDa
- Gene ID
- 55750
- NCBI Accession
- NM_018238, NP_060708
- UniProt
- Q53H12
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