A Kinase (PRKA) Anchor Protein 10 (AKAP10) (Middle Region) Peptide
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- Target See all AKAP10 products
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKAP10 Antibody(ARP36326_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
- Synonyms
- MGC84612 Peptide, AKAP10 Peptide, fc10g11 Peptide, wu:fc10g11 Peptide, si:dkey-197m14.4 Peptide, AKAP-10 Peptide, D-AKAP-2 Peptide, D-AKAP2 Peptide, PRKA10 Peptide, 1500031L16Rik Peptide, B130049N18Rik Peptide, D-akap2 Peptide, Akap10 Peptide, A-kinase anchoring protein 10 Peptide, A-kinase anchoring protein 10 L homeolog Peptide, A kinase (PRKA) anchor protein 10 Peptide, AKAP10 Peptide, akap10.L Peptide, akap10 Peptide, Akap10 Peptide
- Background
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: PDZK1,PRKAR1A,PRKAR2A,PRKAR2B,SLC9A3R1,PDZK1,PRKAR1A
Protein Size: 662 - Molecular Weight
- 71 kDa
- Gene ID
- 11216
- NCBI Accession
- NM_007202, NP_009133
- UniProt
- O43572
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