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Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide

Name: Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide
SKU: ABIN973092
Price: 160.46 USD
Availability: InStock

ALAS1 Reactivity: Human Host: Synthetic BP, WB

(1 reference)

Catalog No. ABIN973092

Quick Overview for Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide (ABIN973092)

ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Human

Synthetic

Blocking Peptide (BP), Western Blotting (WB)

Characteristics

This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Aminolevulinate, delta-, Synthase 1 (ALAS1) peptide
ALAS1 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) peptide
ALAS1 Reactivity: Human Host: Synthetic BP, WB

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Lazareth, Poli, Bignon, Mirmiran, Rabant, Cohen, Schmitt, Puy, Karras, Gouya, Pallet: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
Target

ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Background

Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

Alias Symbols: ALAS, ALAS3, ALASH, MIG4

Protein Interaction Partner: STAMBP

Protein Size: 640

Molecular Weight

70 kDa

Gene ID

211

NCBI Accession

NM_000688, NP_000679

UniProt

P13196

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