Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) Peptide
ALAS1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ALAS1 products
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RALSTAAVHY QQIKETPPAS EKDKTAKAKV QQTPDGSQQS PDGTQLPSGH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALAS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
- Synonyms
- ALAS Peptide, ALAS3 Peptide, ALASH Peptide, MIG4 Peptide, ALAS-N Peptide, Alas-1 Peptide, Alas-h Peptide, ALAS-H Peptide, ALASN Peptide, ALAS1 Peptide, wu:fb58d01 Peptide, wu:fi12g09 Peptide, 5'-aminolevulinate synthase 1 Peptide, aminolevulinic acid synthase 1 Peptide, alanyl-tRNA synthetase protein Peptide, aminolevulinate, delta-, synthase 1 Peptide, ALAS1 Peptide, Alas1 Peptide, alas1 Peptide, alas1.S Peptide, alaS1 Peptide
- Background
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This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: ALAS1, ALAS3, ALASH, OK/SW-cl.121,
Protein Size: 640 - Gene ID
- 211
- NCBI Accession
- XP_005265002
- UniProt
- P13196
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