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Angiopoietin 1 (ANGPT1) (N-Term) Peptide

ANGPT1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973195
  • Target See all Angiopoietin 1 (ANGPT1) products
    Angiopoietin 1 (ANGPT1)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 6
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ANGPT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Angiopoietin 1 (ANGPT1)
    Synonyms
    AGP1 Peptide, AGPT Peptide, ANG1 Peptide, 1110046O21Rik Peptide, Ang-1 Peptide, Ang1 Peptide, Agpt Peptide, Agpt1 Peptide, ang1 Peptide, wu:fc76g06 Peptide, ANG-1 Peptide, angpt1 Peptide, MGC80788 Peptide, angiopoietin 1 Peptide, angiopoietin 1 S homeolog Peptide, ANGPT1 Peptide, Angpt1 Peptide, angpt1 Peptide, angpt1.S Peptide
    Background
    Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Alias Symbols: AGP1, AGPT, ANG1

    Protein Interaction Partner: ANGPT1,ANGPT2,ITGA5,TEK,TEK,TEK

    Protein Size: 498
    Molecular Weight
    55 kDa
    Gene ID
    284
    NCBI Accession
    NM_001146, NP_001137
    UniProt
    Q15389
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