Angiopoietin 1 (ANGPT1) (N-Term) Peptide
ANGPT1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973195
$160.46
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100 μg
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United States
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Quick Overview for Angiopoietin 1 (ANGPT1) (N-Term) Peptide (ABIN973195)
Target
Angiopoietin 1 (ANGPT1)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- FAFLAAILTH IGCSNQRRSP ENSGRRYNRI QHGQCAYTFI LPEHDGNCRE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANGPT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Angiopoietin 1 (ANGPT1) (AA 20-498) peptide
ANGPT1 Reactivity: Human Host: Escherichia coli (E. coli) SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Angiopoietin 1 (ANGPT1)
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Background
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Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AGP1, AGPT, ANG1
Protein Interaction Partner: ANGPT1,ANGPT2,ITGA5,TEK,TEK,TEK
Protein Size: 498 -
Molecular Weight
- 55 kDa
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Gene ID
- 284
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NCBI Accession
- NM_001146, NP_001137
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UniProt
- Q15389
Target
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