Angiopoietin-Like 3 (ANGPTL3) (N-Term) Peptide
ANGPTL3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973199
$160.46
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100 μg
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Quick Overview for Angiopoietin-Like 3 (ANGPTL3) (N-Term) Peptide (ABIN973199)
Target
ANGPTL3
(Angiopoietin-Like 3 (ANGPTL3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- VKILANGLLQ LGHGLKDFVH KTKGQINDIF QKLNIFDQSF YDLSLQTSEI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANGPTL3 Antibody(ARP42411_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
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Background
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The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Alias Symbols: ANGPT5, FHBL2
Protein Interaction Partner: ITGA5,ITGAV,ITGB3
Protein Size: 460 -
Molecular Weight
- 51 kDa
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Gene ID
- 27329
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NCBI Accession
- NM_014495, NP_055310
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UniProt
- Q9Y5C1
Target
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