Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (Middle Region) Peptide
ASH2L
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN973509
Quick Overview for Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (Middle Region) Peptide (ABIN973509)
Target
ASH2L
(Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ASH2L antibody (Catalog #: ARP34202_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
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Background
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ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: DPY30,MEN1,MLL,MLL2,SMAD9,SMURF1,SMURF2,TGFBR1,UNC119,ASH2L,CHD8,CXXC1,DPY30,HCFC1,HCFC2,HIST3H3,KDM6A,MEN1,MLL,MLL3,MYB,PHF8,RBBP5,SETD1A,UNC119,WDR5,WDR82P1
Protein Size: 628 -
Molecular Weight
- 69 kDa
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Gene ID
- 9070
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NCBI Accession
- NM_004674, NP_004665
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UniProt
- Q9UBL3
Target
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