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Aurora Kinase A (AURKA) Peptide

AURKA Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN973656
  • Target See all Aurora A (AURKA) products
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AURKA antibody (Catalog #: ARP30876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Synonyms
    AIK Peptide, ARK1 Peptide, AURA Peptide, AURORA2 Peptide, BTAK Peptide, PPP1R47 Peptide, STK15 Peptide, STK6 Peptide, STK7 Peptide, AIRK1 Peptide, AU019385 Peptide, AW539821 Peptide, Ark1 Peptide, Aurora-A Peptide, Ayk1 Peptide, IAK Peptide, IAK1 Peptide, Stk6 Peptide, 87A7-9/2 Peptide, Aur-A Peptide, AurA Peptide, CG3068 Peptide, Dmel\\CG3068 Peptide, aur-A Peptide, aurA Peptide, ck10 Peptide, ck[10] Peptide, l(3)87Ac Peptide, l(3)ck10 Peptide, ARK-1 Peptide, Eg2 Peptide, aik Peptide, ark1 Peptide, aur-a Peptide, aura Peptide, aurka-a Peptide, aurora2 Peptide, btak Peptide, stk15 Peptide, stk6 Peptide, stk7 Peptide, pEg2 Peptide, wu:fb37c10 Peptide, wu:fc02c02 Peptide, zgc:100912 Peptide, AURKA Peptide, aurka Peptide, aurora kinase A Peptide, aurora A Peptide, aurora kinase A L homeolog Peptide, hypothetical protein Peptide, aurora kinase A S homeolog Peptide, AURKA Peptide, Aurka Peptide, aurA Peptide, aurka.L Peptide, aurka Peptide, Aurora-A Peptide, aurka.S Peptide
    Background
    AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

    Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7, PPP1R47

    Protein Interaction Partner: CHFR,RASA1,TP53,AURKA,AURKAIP1,BRCA1,C13orf34,CDC20,CDC25B,CHFR,CKAP5,GSK3B,MBD3,NDC80,NIN,NME1,NUF2,PML,PPP1CA,PPP1CC,PRKACA,TACC1,TACC3,TP53,TPX2,UBE2N,BRCA1,CDC20,CDKN2A,CHFR,KIF2C,MBD3,NFKBIA,NIN,NME1,PML,RAB10,SOD2,TACC1,TP53,TPX2,UBE2L3,UBE2N

    Protein Size: 403
    Molecular Weight
    46 kDa
    Gene ID
    6790
    NCBI Accession
    NM_003600, NP_003591
    UniProt
    O14965
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