Beta-secretase 1 (BACE1) (Middle Region) Peptide
BACE1
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN973701
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Beta-secretase 1 (BACE1) (Middle Region) Peptide (ABIN973701)
Target
BACE1
(Beta-secretase 1 (BACE1))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Bace1 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Background
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Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Alias Symbols: C76936
Protein Size: 501 -
Molecular Weight
- 56 kDa
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Gene ID
- 23821
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NCBI Accession
- NM_011792, NP_035922
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UniProt
- P56818
Target
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