BCL2-Associated Athanogene (BAG1) (N-Term) Peptide
BAG1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BAG1 products
- BAG1 (BCL2-Associated Athanogene (BAG1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LIFKGKSLKE METPLSALGI QDGCRVMLIG KKNSPQEEVE LKKLKHLEKS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BAG1 (BCL2-Associated Athanogene (BAG1))
- Synonyms
- BAG-1 Peptide, HAP Peptide, RAP46 Peptide, Rap46 Peptide, Bag-1 Peptide, ATBAG1 Peptide, BCL-2-associated athanogene 1 Peptide, MSG15.15 Peptide, MSG15_15 Peptide, im:7148830 Peptide, si:dkey-216e9.4 Peptide, BCL2 associated athanogene 1 Peptide, putative bcl2-associated athanogene Peptide, BCL2-associated athanogene 1 Peptide, Bcl2 associated athanogene 1 Peptide, BAG family molecular chaperone regulator 1 Peptide, BCL-2-associated athanogene 1 Peptide, BAG1 Peptide, Smp_005900 Peptide, Bag1 Peptide, bag-1 Peptide, LOC781741 Peptide, bag1 Peptide
- Background
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: HSPA4,AR,BCL2,BCL2L1,ESR1,HBEGF,HSPA1A,HSPA1B,HSPA8,MET,NR3C1,PDGFRB,PPP1R15A,PSMD1,RAF1,RARA,RB1,SIAH1,STUB1,VDR,AR,BCL2,ESR1,HBEGF,HSPA1A,HSPA4,HSPA8,MAPT,NR3C1,PPP1R15A,RAF1,RARA,RB1,SIAH1,STUB1,TP53,UBC,VDR
Protein Size: 230 - Molecular Weight
- 25 kDa
- Gene ID
- 573
- NCBI Accession
- NM_001172415, NP_001165886
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