Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (Middle Region) Peptide
CASP10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974472
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (Middle Region) Peptide (ABIN974472)
Target
Caspase 10 (CASP10)
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequence
- HNNVTKVEME MVLQKQKCNP AHADGDCFVF CILTHGRFGA VYSSDEALIP
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-CASP10 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
-
Background
-
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ALPS2, FLICE2, MCH4
Protein Interaction Partner: RB1,BFAR,BID,CASP10,CASP14,CASP2,CASP3,CASP4,CASP6,CASP7,CASP8,CASP9,CCAR1,CFLAR,DEDD,DEDD2,DSP,FADD,POLR2A,RB1,RYBP,TNFRSF1A,TRAF1,AIF1,ARHGDIA,BID,CASP1,CASP10,CASP14,CASP2,CASP3,CASP4,CASP6,CASP7,CASP8,CASP9,CFLAR,DEDD,DEDD2,EZR,FADD,FAS,FASLG,MAP3K14,
Protein Size: 479 -
Molecular Weight
- 12 kDa
-
Gene ID
- 843
-
NCBI Accession
- NM_001230, NP_001221
-
UniProt
- Q92851
Target
-
You are here:
