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Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (Middle Region) Peptide

CASP6 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974477
  • Target See all Caspase 6 (CASP6) products
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CASP6 Antibody(ARP58994_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Synonyms
    xCaspase-6 Peptide, mch2 Peptide, caspase-6 Peptide, zgc:112960 Peptide, CASP6 Peptide, casp6 Peptide, Mch2 Peptide, mCASP-6 Peptide, MCH2 Peptide, caspase 6 L homeolog Peptide, caspase 6 Peptide, caspase 6, apoptosis-related cysteine peptidase Peptide, group XIIA secretory phospholipase A2 Peptide, caspase-6 Peptide, casp6.L Peptide, casp6 Peptide, CASP6 Peptide, CpipJ_CPIJ017008 Peptide, Casp6 Peptide
    Background
    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

    Alias Symbols: MCH2

    Protein Interaction Partner: HTT,RB1,APP,CASP10,CASP3,CASP8,CFLAR,CHD3,DSP,EIF2S1,HTT,KRT18,LMNA,LMNB1,MAPT,NEDD4,NUAK1,PCYT1A,PPL,PRKCZ,PSEN1,PSEN2,PSME3,RB1,SATB1,SRF,SRP72,TFAP2A,TOP1,TRAF1,UBE4B,VIM,BIRC6,CASP10,CASP3,CASP6,CASP8,CHD3,TRAF1,XIAP

    Protein Size: 293
    Molecular Weight
    11 kDa
    Gene ID
    839
    NCBI Accession
    NM_001226, NP_001217
    UniProt
    P55212
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