Centromere Protein M (CENPM) (Middle Region) Peptide
CENPM
Reactivity: Human
Host: Synthetic
BP, WB, ICC
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- Target See all CENPM products
- CENPM (Centromere Protein M (CENPM))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CENPM antibody (Catalog #: ARP46323_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CENPM (Centromere Protein M (CENPM))
- Synonyms
- C22orf18 Peptide, CENP-M Peptide, PANE1 Peptide, bK250D10.2 Peptide, 2610019I03Rik Peptide, AI853711 Peptide, Pane1 Peptide, RGD1307309 Peptide, centromere protein M Peptide, centromere protein M L homeolog Peptide, Centromere protein M Peptide, centromere protein M pseudogene Peptide, CENPM Peptide, Cenpm Peptide, cenpm Peptide, cenpm.L Peptide, LOC100353362 Peptide
- Background
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The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].
Alias Symbols: C22orf18, CENP-M, MGC861, PANE1, bK250D10.2
Protein Size: 180 - Molecular Weight
- 20 kDa
- Gene ID
- 79019
- NCBI Accession
- NM_024053, NP_076958
- UniProt
- Q9NSP4
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