Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1) Peptide
CHST1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN974966
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1) Peptide (ABIN974966)
Target
CHST1
(Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHST1 antibody (Catalog #: ARP45495_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))
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Background
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CHST1 catalyzes the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. It may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.
Alias Symbols: C6ST, KS6ST, KSGal6ST, KSST, GST-1
Protein Interaction Partner: SFN,SFN
Protein Size: 411 -
Molecular Weight
- 47 kDa
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Gene ID
- 8534
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NCBI Accession
- NM_003654, NP_003645
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UniProt
- O43916
Target
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