Cannabinoid Receptor 1 (CNR1) (N-Term) Peptide
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- Target See all CNR1 products
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ADQVNITEFY NKSLSSFKEN EENIQCGENF MDIECFMVLN PSQQLAIAVL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CNR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Synonyms
- CANN6 Peptide, CB-R Peptide, CB1 Peptide, CB1A Peptide, CB1K5 Peptide, CB1R Peptide, CNR Peptide, SKR6R Peptide, cnr1-A Peptide, cannabinoid receptor 1 Peptide, cannabinoid receptor 1 (brain) Peptide, cannabinoid receptor 1 (brain) S homeolog Peptide, CNR1 Peptide, Cnr1 Peptide, cnr1 Peptide, cnr1.S Peptide
- Background
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This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.
Alias Symbols: CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Protein Interaction Partner: HIST4H4,PAX3,GNA15,GNAI1,GNAI2,GNAI3,HCRTR1,MET,GNAI1,GNAI2,GNAI3
Protein Size: 411 - Molecular Weight
- 45 kDa
- Gene ID
- 1268
- NCBI Accession
- NM_016083, NP_057167
- UniProt
- P21554
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