Cortistatin (CORT) (N-Term) Peptide
CORT
Reactivity: Human
Host: Synthetic
WB, BP
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- Target See all CORT products
- CORT (Cortistatin (CORT))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- MPLSPGLLLL LLSGATATAA LPLEGGPTGR DSEHMQEAAG IRKSSLLTFL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CORT Antibody(ARP59541_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
Cortistatin (CORT) peptide (Ovalbumin)
CORT Reactivity: Human Host: Synthetic WB, Imm, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CORT (Cortistatin (CORT))
- Synonyms
- CST-14 Peptide, CST-17 Peptide, CST-29 Peptide, CST Peptide, PCST Peptide, cortistatin Peptide, CORT Peptide, Cort Peptide
- Background
-
This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.
Alias Symbols: CST-14, CST-17, CST-29
Protein Interaction Partner: GHSR,MRGPRX2,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5,SSTR1,SSTR2,SSTR3,SSTR4,SSTR5
Protein Size: 155 - Molecular Weight
- 2 kDa
- Gene ID
- 1325
- NCBI Accession
- NM_001302, NP_001293
- UniProt
- O00230
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