Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Peptide
CXCR4
Reactivity: Human
Host: Synthetic
BP, WB, IHC, FACS
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- Target See all CXCR4 products
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCR4 antibody (Catalog #: ARP30799_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 26-37) peptide (Ovalbumin)
CXCR4 Reactivity: Human Host: Synthetic WB, Imm, SDS
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Synonyms
- CD184 Peptide, D2S201E Peptide, FB22 Peptide, HM89 Peptide, HSY3RR Peptide, LAP3 Peptide, LCR1 Peptide, LESTR Peptide, NPY3R Peptide, NPYR Peptide, NPYRL Peptide, NPYY3R Peptide, WHIM Peptide, Cmkar4 Peptide, PB-CKR Peptide, PBSF/SDF-1 Peptide, Sdf1r Peptide, CXC-R4-B Peptide, CXCR-4-B Peptide, cd184 Peptide, cxcr4 Peptide, fb22 Peptide, hm89 Peptide, hsy3rr Peptide, lap3 Peptide, lcr1 Peptide, lestr Peptide, npy3r Peptide, npyr Peptide, npyrl Peptide, npyy3r Peptide, xcxcr4 Peptide, CXC-R4 Peptide, CXCR-4 Peptide, d2s201e Peptide, whim Peptide, CXC-R4-A Peptide, CXCR-4-A Peptide, xCXCR4 Peptide, CXCR4 Peptide, cb403 Peptide, zgc:109863 Peptide, cb824 Peptide, C-X-C motif chemokine receptor 4 Peptide, chemokine (C-X-C motif) receptor 4 Peptide, C-X-C motif chemokine receptor 4 S homeolog Peptide, C-X-C chemokine receptor type 4 Peptide, C-X-C motif chemokine receptor 4 L homeolog Peptide, chemokine (C-X-C motif), receptor 4b Peptide, chemokine (C-X-C motif) receptor 4a Peptide, CXCR4 Peptide, Cxcr4 Peptide, cxcr4.S Peptide, cxcr4 Peptide, LOC100049444 Peptide, cxcr4.L Peptide, cxcr4b Peptide, cxcr4a Peptide
- Background
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CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Protein Interaction Partner: CXCL12,ADRBK2,ARRB2,CCR5,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,GNA13,GNAI1,HSPA8,JAK1,JAK2,JAK3,MYH9,PTK2,PTPN11,PTPN6,PTPRC,SDC4,SOCS1,SOCS3,STAT1,STAT2,STAT3,STAT5B,VAV1,ADRBK2,CCR5,CD4,ITCH,JAK2,JAK3,PTK2,PTPN6,SOCS3,UBC,USP14
Protein Size: 352 - Molecular Weight
- 40 kDa
- Gene ID
- 7852
- NCBI Accession
- NM_003467, NP_003458
- UniProt
- P61073
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