Deoxycytidine Kinase (DCK) (Middle Region) Peptide
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- Target See all DCK products
- DCK (Deoxycytidine Kinase (DCK))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCK antibody (Catalog #: ARP51774_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DCK (Deoxycytidine Kinase (DCK))
- Synonyms
- dck Peptide, DCK Peptide, wu:fc15f06 Peptide, zgc:101771 Peptide, dck1 Peptide, deoxycytidine kinase Peptide, deoxycytidine kinase, gene 2 L homeolog Peptide, deoxycytidine kinase, gene 2 Peptide, Deoxycytidine kinase Peptide, deoxycytidine kinase, gene 1 L homeolog Peptide, DCK Peptide, dck Peptide, dck.2.L Peptide, dck.2 Peptide, Dck Peptide, FPV059 Peptide, FPV151 Peptide, dck.1.L Peptide
- Background
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Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117410, MGC138632
Protein Interaction Partner: DDX19B,GOLM1,MED19,DDX19B,GOLM1,MED19
Protein Size: 260 - Molecular Weight
- 30 kDa
- Gene ID
- 1633
- NCBI Accession
- NM_000788, NP_000779
- UniProt
- P27707
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